Epidemiology and Pathophysiology 
Prevalence of Diabetes
Economic Burden of Diabetes
Type 1 Diabetes
Natural History of Type 1 Diabetes
Late-Onset Type 1 Diabetes
Teaching Point
The Dual Defect of Type 2 Diabetes
Exacerbation of Hyperglycemia in Type 2 Diabetes
Pathogenesis of Type 2 Diabetes
Insulin Resistance
Impaired Glucose Tolerance and Type 2 Diabetes
Differences in Insulin Secretion
Free Fatty Acids in Hyperglycemia
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Prevalence of Diabetes
  • In the USA there are approximately 17 milllion people with diabetes.

  • Approximately 10% have type 1 diabetes.

  • Of the remaining 90% with type 2 diabetes almost 1/3 are unaware that they have the disease.