photo of Loring, Stephen H

Stephen H Loring, MD

Professor
Anesthesia
Contact Information
Office:   DA-0717
Phone:   617-667-3092
Fax:   617-667-1500
Email:   sloring@bidmc.harvard.edu
Address:    330 Brookline Ave; DA-0717
 Boston, MA 02215
Major Research Theme
Our respiratory physiology laboratory supports research in two areas.  The first area is applied respiratory physiology and respiratory mechanics in normal subjects and patients with a variety of lung diseases.  Currently, we are exploring the mechanisms of chest wall-lung interaction in patients with emphysema and other patients undergoing lung volume reduction surgery and lung transplantation.  We have recently begun an investigation of the role of chest wall restriction in critically all patients with acute lung injury, and have several other studies developing and evaluating tests of pulmonary function.  We are also studying the physiology of tracheomalacia in concert with the interventional pulmonary program and techniques for early diagnosis of CHF with members of the Emergency Department.  The secondary area is biomechanics and physiology of the pleural space.  We are exploring the mechanisms whereby the lung and chest wall can slide against each other during breathing without damage.  These studies entail computational fluid mechanics and finite element analysis, biochemical measurements on tissues, and in vitro and histological studies in animal tissues.
External Recognition
1998-2002 Member, Respiratory and Applied Physiology/Respiratory Physiology Study Section, NIH.
2000-2008  Member, Observational study monitoring board, Sleep Heart Health Study, NHLBI
2005-2006       Respiratory Integrative Biology and Translational Research study section, NIH, Ad-Hoc Member, National Institutes of Health
Major Collaborative Activities
Collaboration with thoracic surgeons and pulmonary physicians at Brigham and Women's Hospital in NIH funded research on respiratory disease.

Collaboration with physiologists in Milan on animal experiments measuring intereactions between the lung and chest wall.
Investigator's Lab Web Site
Research Lab URL     None listed
Harvard Catalyst Site:     Loring Harvard Catalyst Web Site