Theodore I Steinman, MD
Physician, Professor
Nephrology
Contact Information
| Office: | ST-0220 |
| Phone: | 617-667-5278 |
| Fax: | 617-975-5595 |
| Email: | tsteinma@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; ST-0220
Boston, MA 02215 |
Advanced Degree And Training
| Year | Institution | Area or Rank |
| 1964 | Georgetown | MD |
| 1993 | HMS | Prof of Medicine |
Research Lab Team Members
| John Danziger MD |
Major Research Theme
| Dr. Steinman has been engaged in polycystic kidney disease research for the past many years. A study was completed which documented the relationship between cyst volume and glomerular filtration rate in patients with autosomal dominant polycystic kidney disease (ADPKD). He is now embarking on an NIH sponsored multi-centered study examining the inter-relationship between blood pressure, cyst volume, total kidney volume and renal blood flow (measured via an MRA technique) in ADPKD patients. Therapeutic interventions will investigate the renin-angiotensin axis as a factor in predicting progression of renal disease in the hypertensive ADPKD patient. The study will also examine the renin-angiotensin axis in the normotensive ADPKD patient, and determine if this humoral axis plays a role in progression independent of the blood pressure. Two groups will be studied, those with a calculated (via the modified MDRD equation) GFR of 30-60 cc/min and those whose GFR is >60 cc/min. Ancillary studies will also be conducted, depending on the total funding available. This 5 year project will allow a renal fellow interested in clinical research to be immersed in the clinical care of this study population, and understand the nuisances involved in doing detailed clinical investigation. At the same time, knowledge will be gained about the pathophysiology of ADPKD, the issue of genomics and therapeutic interventions in a field that is rapidly evolving. The HALT PKD study group is part of an NIH-sponsored therapeutic network. More cooperative studies will follow this initial investigation. |
Publications
External Recognition
| 1995 Outstanding Physician of the Year, National Kidney Foundation of Massachusetts and Rhode Island 1996 Alumni Fellow of the Year, Pennsylvania State University 2000 Jared J.Grantham Distinguished Achievement Award, Polycystic Kidney Research Foundation 2001 Intellectuals of the 21st Century, Cambridge, England 2003 Listed in Consumers Research: Guide to America’s Top Physician 2004 Outstanding Service Award, National Kidney Foundation of Massachusetts, Rhode Island, New Hampshire and Vermont 1992-2008 Best Doctors in America 2008 Certificate of Appreciation, Beth Israel Deaconess Medical Center 2008 S. Robert Stone Senior Award for Excellence in Teaching, Harvard Medical School 2008 2008 Nominee, Harvard Medical School Prize for Excellence in Teaching Years, I & II) |
Investigator's Lab Web Site
| Research Lab URL | None listed |
| Harvard Catalyst Site: | Steinman Harvard Catalyst Web Site |
