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BIDMC Research Investigator / Faculty Information

Bruce Dezube MD

Associate Professor

Hematology and Oncology

Faculty Appointment:

Hematology and Oncology

   

Contact Information:

Bruce Dezube MD
Title:   Physician Assoc Professor
Office:   MB-416
Phone:   617-632-9268
Fax:   617-632-9296
Email:   bdezube@bidmc.harvard.edu
Address:   Beth Israel Deaconess Medical Center
 330 Brookline Ave; MB-416
 Boston, MA 02215

Advanced Degree And Training Info:

Year

Institution

Area or Rank


No data available

Research Team Listing

No team members listed

Areas of Interest:

Cancer & Hematologic

Infectious Diseases, Inflammation Patient Oriented / Translational Vascular Biology

Major Research Theme:

My group does both clinical and translational research.  My patient population consists of cancer patients and HIV-infected patients.  My clinical research spans two separate programs-- 1) AIDS Malignancy Research and Treatment Center (funded through the AIDS Malignacy Consortium of the NCI) and 2) drug development (Experimental Therapeutics/Phase I Program through the DF/HCC).

Select Major Publications:    List of Publications via PubMed database at NIH NLM

Sullivan RJ, Pantanowitz L, Casper C, Stebbing J, Dezube BJ. HIV/AIDS: epidemiology, pathophysiology, and treatment of kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma, and multicentric castleman disease. Clin Infect Dis. 2008;47:1209-15.
Dezube BJ, Krown SE, Lee JY, Bauer KS, Aboulafia DM. Randomized phase II trial of matrix metalloproteinase inhibitor COL-3 in AIDS-related Kaposi's sarcoma: an AIDS Malignancy Consortium Study.
J Clin Oncol. 2006;24:1389-94.
Di Lorenzo G, Konstantinopoulos PA, Pantanowitz L, Di Trolio R, De Placido S, Dezube BJ. Management of AIDS-related Kaposi's sarcoma. Lancet Oncol. 2007;8:167-76
Miles SA, Dezube BJ, Lee JY, Krown SE, Fletcher MA, Saville MW, Kaplan L, Groopman J, Scadden DT, Cooley T, Von Roenn J, Friedman-Kein A for AIDS Malignancy Consortium. Antitumor activity of oral 9-cis-retinoic acid in HIV-associated Kaposi's sarcoma. AIDS 2002; 16:421-429.

Dezube BJ, Dahl TA, Wong TK, Chapman B, Ono M, Yamaguchi N, Gillies SD, Chen LB, Crumpacker CS.  A fusion inhibitor (FP-21399) for the treatment of human immunodeficiency virus infection: A Phase I study. J Infect Dis 2000; 182:607-610.

External Recognition:

1995-      Kaposi Sarcoma Committee, AIDS Malignancy Consortium/NCI/NIH
        (From 1999-2001, I was the elected co-chair of this committee
         From 2002-2004, I am the chair of this committee)
1995-      Non-Hodgkin Lymphoma Committee, AIDS Malignancy Consortium/NCI/NIH
1998-      Human Papilloma Virus Committee, AIDS Malignancy
         Consortium/NCI/NIH
1995-      AIDS-Associated Malignancies, Clinical Trials Consortium Award, National Cancer Institute
1996      Greater Boston Business Council, Finalist for AIDS Service Award
1999      Letter of Recognition from Chairman of Medicine for Excellence in
         Teaching
2001      Letter of Recognition from the National Medical Association for
         Excellence in Service

Major Collaborative Activities:

I am the Principal Investigator of the AIDS-Associated Malignancies Consortium Award/National Cancer Institute.
I have published many papers with investigators at MGH, including David Scadden and Michael Detmar.
I have ongoing collaboration which have yielded papers with approximately a dozen investigators at BIDMC (Joyce Fingeroth, Clyde Crumpacker, John Doweiko, Jerome Groopman,...)

Investigator's Web Site:

             

Harvard Catalyst Site:

   
 

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