The focus of my laboratory has been the investigation of the autonomic control of cardiovascular function. We have in particular focused on baroreflex control, venous function and the cutaneous blood flow. We have used cutaneous blood flow as a model to examine autonomic control at the neurovascular junction and small fiber function.
Farquhar WB, Taylor JA, Darling S, Chase KP, Freeman R. Abnormal baroreflex responses in patients with idiopathic orthostatic intolerance. Circulation 102:3086-3091, 2000
Kilo S, Berghoff M, Hilz MJ, Freeman R. Neural and endothelial control of the cutaneous microcirculation in diabetic peripheral neuropathy. Neurology 54:1246-1252, 2000.
Farquhar WB, Hunt B, Taylor JA, Freeman R. Blood volume and its relation to peak oxygen consumption and physical activity in patients with chronic fatigue. American Journal of Physiology 2002; 282: H66-71.
Berghoff M, Kathpal M, Kilo S, Hilz MJ, Freeman R. Vascular and neural mechanisms of acetylcholine mediated vasodilation in the forearm cutaneous microcirculation. Journal of Applied Physiology 2002; 92: 780-788.
Freeman R, Lirofonis V, Farquhar WB, Risk M. Limb venous compliance in patients with idiopathic orthostatic intolerance and postural tachycardia. Journal of Applied Physiology 2002; (In press)
External Recognition:
1996-1998 Chairman - Section of the Autonomic Nervous System, American Academy of Neurology
1998-2000 President, American Autonomic Society
