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BIDMC Research Investigator / Faculty Information

Bruce Furie MD

Professor

Hemostasis Thrombosis

Faculty Appointment:

Hemostasis Thrombosis

Medicine

  

Contact Information:

  
Title:   Physician Professor Co-Chief
Office:   CLS-0903
Phone:   735-4002
Fax:   735-4000
Email:   bfurie@bidmc.harvard.edu
Address:   Beth Israel Deaconess Medical Center
 330 Brookline Ave; CLS-0903
 Boston, MA 02215

Advanced Degree And Training Info:

Year

Institution

Area or Rank

1970  University of Pennsylvania School of Medicine  Medicine
1970  Hospital of the University of Pennsylvania  Resident
1972  NIH  Research Associate
1974  SUNY Upstate Medical Center  Fellow
1975  Tufts University School of Medicine  Chief Hematology-Oncology
1997  BIDMC  Director Cancer Center
1997  BIDMC/Harvard  Professor

Research Team Listing

Juanita Caine

Vivien Chen MD,PhD Mingdong Huang PhD Lin Lin PhD

Jacky Ngo PhD

 Cameron Trenor MD Jeffrey Zwicker MD

Areas of Interest:

Cancer & Hematologic

 Cardiovascular Infectious Diseases, Inflammation Patient Oriented / Translational

Vascular Biology

    

Major Research Theme:

Role of P-selectin and PSGL-1 in leukocyte-endothelial cell interaction

Thrombus formation and the role of tissue factor

Gamma-carboxyglutamic acid:  vitamin K-dependent synthesis and function

Factor VIII and Factor IX structure and function

Thrombosis and cancer

Microparticles and their function in blood coagulation

Intravital microscopy and the study of thrombus formation

Select Major Publications:    List of Publications via PubMed database at NIH NLM

Furie, B. And Furie, B.C.: Thrombus formation in vivo.  J. Clin. Invest. 115:3355-3362, 2005.

Ngo, J., Huang, M., Roth, D.A., Furie, B.C. and Furie, B.:  Crystal structure of human factor VIII: Implications for the formation of the factor IXa-factor VIIIa complex.  Structure 16:597-606,  2008.
Dubois, C., Panicot-Dubois, L., Gainor, J.F., Furie, B.C. and Furie, B.:  Thrombin-initiated platelet activation in vivo is von Willebrand factor-independent during thrombus formation in a laser injury model.  J. Clin. Invest. 117:953-960, 2007..
Cho, J., Furie, B.C., Coughlin, S. and Furie, B.:  A critical role for extracellular protein disulfide isomerase during thrombus formation in vivo.  J. Clin. Invest. 118:1123-1131, 2008.
Furie, B. and Furie, B.C.: Mechanisms of thrombus formation.  N. Engl. J. Med. 359:938-949, 2008.

External Recognition:

President,  International Society for Thrombosis and Haemostasis
Honorary MD Degree. 2003, University of Lund, Lund Sweden
Reneman Lecturer, 2008, Cardiovascular Research Institute, Maastricht University, Maastricht, The Netherlands
Desire Collen Foundation Plenary Lectureship, XXI Congress of the ISTH, Geneva Switzerland, 2007
Editorial Boards:  BLOOD, Molecular Medicine, J. Thromb. Haemost., Hem-Onc Today

Major Collaborative Activities:

Dr. Simon Robson
Dr. Rob Flaumenhaft
Dr. Barbara C. Furie
Dr. Mingdong Huang

Investigator's Web Site:

              

Harvard Catalyst Site:

    
 

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