My primary clinical research focuses on the natural history of early or presymptomatic multiple sclerosis with an attempt to understand risk factors and predictors associated with disease activity and progression.
Secondary research focuses on clinical trials of therapeutics in Multiple sclerosis.
1. Kinkel RP, Kollman C, O'Connor PW and the CHAMPIONS investigator group. IM Interferon Beta 1a delays definite Multiple Sclerosis 5-years after a first demyelinating event. Neurology 2006; 66: 678-684.
2. Kinkel RP, Beck R, Jacobs L, et al Predictors of Short-term Disease Activity Following a First Clinical Demyelinating Event: Analysis of the CHAMPS Placebo Cohort. Multiple Sclerosis 2002;8:405-409.
3. Simon JH, Kinkel RP, Jacobs L, et al. Transcallosal bands; A sign of tract degeneration in early MS? Neurol 2001;57:1888-90.
4. Tuohy VK, Yu M, Ling Y, Kawczak JA, Kinkel RP. Spontaneous regression of primary autoreactivity during chronic progression of Experimental autoimmune encephalomyelitis and multiple sclerosis.
J. Exp. Med. 1999;189(7):1033-1042.
5. Kinkel RP, Simon J, Baron J. Bimonthly cranial MRI activity following an isolated monosymptomatic demyelinating syndrome: Potential MR outcome measures for future Multiple Sclerosis ?prevention? trials. Multiple Sclerosis 1999;5:307-12.
External Recognition:
1. Scientific study Section, National Multiple Sclerosis Society
2. National Multiple Sclerosis Society Medical Advisory Panel
Major Collaborative Activities:
1. Collaboration with Lisa Iezzoni on an NMSS contract related to national health care outcomes in MS
2. Collaboration with Dr Bruce Rosen at Martino Center to study novel MR metrics in MS
