Roth DA, Tawa NE, O’Brien JM, Treco DA, Selden RF. Nonviral transfer of the gene encoding coagulation factor VIII in patients with severe hemophilia A. New England Journal of Medicine 2001;344:1735-42.
Roth DA, Kessler CM, Pasi KJ, Rup B, Courter SG, Tubridy K. Human recombinant factor IX: Safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates. Blood 2001;98:3600-6.
Romero EE, Niman ZE, Qu D, Roth DA. A novel upstream promoter element is required for vitamin K-dependent g-glutamyl carboxylase gene expression in rat hepatoma cells. Blood 1999,94: (Suppl. 1),647.
Boudakov I, Marvi U, Niman ZE, Romero EE, Roth DA In vivo analysis of the vitamin K-dependent g-glutamyl carboxylase gene promoter. Blood 2001, 98:(Suppl 1), 824.
Romero EE, Deo R, Velazquez-Estades LJ, Roth DA. Cloning, structural organization and transcriptional activity of the rat vitamin K-dependent g-glutamyl carboxylase gene. Biochemical and Biophysical Research Communications 1998;248:783-8.
Romero EE, Velazquez-Estades LJ, Deo R, Schapiro B, Roth DA. Cloning of rat vitamin K-dependent g-glutamyl carboxylase and developmentally regulated gene expression in post-implantation embryos. Experimental Cell Research 1998;243:334-46.
External Recognition:
Awards:
1991 Physician Scientist Award, National Institutes of Health - NHLBI
1996 Basil O'Connor Scholar Award, March of Dimes National Birth Defects Foundation
1997 F.I.R.S.T. Award, National Institutes of Health - NHLBI
2000 Young Investigator Award - Advances in Mineral Metabolism Meeting
2001 Prize on Congenital Coagulation Disorders, Fondazione Angelo Bianchi Bonomi, Milan, Italy
Presentations:
2001 German Society of Thrombosis and Haemostasis (GTH) National Congress - Model Systems in Gene Therapy: Hopes for Hemophiliacs
Duesseldorf, Germany
2001 Gene Therapies for Hemophilia, 4th Workshop FVIII Gene Transfer in Patients with Hemophilia A. The Salk Institute for Biological Studies, La Jolla, California
2001 FASEB Summer Research Conferences: Vitamin K Carboxylase Gene Transcription in Developing Liver, Vermont Academy, Saxtons River, Vermont
2001 National Hemophilia Foundation, Annual National Meeting: Nonviral Transfer of the Factor VIII Gene in Patients with Hemophilia A. Nashville, TN
2002 Annual Region II Hemophilia Treatment Center Meeting. Hemophilia Gene Therapy, Cornell University, Ithaca, New York
2002 American Society of Gene Therapy, 5th Annual Meeting. Plasmid Based Gene Therapy for Hemophilia A. Boston, MA
2002 11th Triennial Congress on Hemophilia. Gene Therapy for the Hemophilias. Angelo Bianchi Bonomi Hemophilia and Thrombosis Foundation. Milan, Italy
Committee Assignments.
Harvard University
1999- Committee on Microbiological Safety & Regulation of Hazardous Biological Agents
1999- Human Gene Therapy Advisory Committee, COMS-CRHBA
National Hemophilia Foundation
2002- Research Grants Review Committee
National Institutes of Health
2002 NHLBI Special Emphasis Panel - Transfusion Medicine/Hemostasis Clinical Research Network Scientific Review Group
