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BIDMC Research Investigator / Faculty Information

Clifford B Saper MD,PhD

Professor

Neurology

Faculty Appointment:

Neurology

   

Contact Information:

Clifford B Saper MD,PhD
Title:   Physician, Professor
Office:   KS-406
Phone:   667-2622
Fax:   975-5161
Email:   csaper@bidmc.harvard.edu
Address:   Beth Israel Deaconess Medical Center
 330 Brookline Ave; KS-406
 Boston, MA 02215

Advanced Degree And Training Info:

Year

Institution

Area or Rank

1977  Washington University  Neurobiology
1981  Washington University  Associate Professor
1985  University of Chicago  Professor
1992  BIDMC  Professor

Research Team Listing

Elda Arrigoni PhD

Xi Chen Minh Ha BS Quan Ha MD

Jun Lu MD,PhD

David Sherman Nina Vujovic Kyoko Yoshida

Areas of Interest:

Neuroscience, Neurobiology, CNS

   

Major Research Theme:

1.) Brain circuitry regulating wakefulness and sleep and circadian rhythms
2.) Brain circuitry regulating CNS response to immune stimuli
3.) Brain circuitry regulating feeding and body weight
4.) Disruption of brain circuitry in neurological degenerative disorders

Select Major Publications:    List of Publications via PubMed database at NIH NLM

Fuller, P.M., Lu, J., Saper, C.B. (2008) Differential rescue of light- and food-entrainable circadian rhythms.  Science 320:1074-1077.
Lu, J., Nelson, L.E., Franks, N., Maze, M., Chamberlin, N.L., Saper, C.B. (2008) Role of endogenous sleep-wake and analgesic systems in anesthesia.  J. Comp. Neurol. 508:648-662.
Lazarus, M., Yoshida, K., Coppari, R., Bass, C.E., Mochizuki, T., Lowell, B.B., Saper, C.B. (2007) EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses.  Nature Neuroscience 10:1131.
Lu, J., Sherman, D., Devor, M., Saper, C.B. (2006) A putative flip-flop switch for control of REM sleep.  Nature 441:589-594.
Gooley, J.J, Schomer, A., Saper, C.B. (2006) The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat. Neurosci. 9:398-407.

External Recognition:

McKnight Scholar Award
Javits Neuroscience Investigator, NINDS
Distinguished Alumnus Award, Washington Univ. Med. Sch.
Councilor, American Neurological Association
Chair, Program Committee, Society for Neuroscience
Chair, Program Committee, American Neurological Assocation
Publication Committee, Society for Neuroscience
Editor-in-chief, Journal of Comparative Neurology
Fellow, Royal College of Physicians

Major Collaborative Activities:

1.) Work with Q. Tong, Brad Lowell in BIDMC Endocrinology on brain circuitry that regulates feeding and body weight.
2.) Work with T.Scammell, N. Chamberlin, and J. Lu in BIDMC Neurology on sleep circuitry.

Investigator's Web Site:

             

Harvard Catalyst Site:

   
 

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