Beth Israel Deaconess Medical Center 330 Brookline Ave; KS-450
Boston, MA 02215
Advanced Degree And Training Info:
Year
Institution
Area or Rank
1998
The Ohio State College of Medicine
Neuropharmacology (PhD)
2002
Beth Israel Deaconess Medical Center
Instructor
Research Team Listing
No team members listed
Areas of Interest:
Gerontology / Aging
Neuroscience, Neurobiology, CNS
Major Research Theme:
My research interests include dementia, delirium, neuropharmacology, and functional imaging. My current research efforts are focused on studying the utility of combined pharmacologic manipulation and arterial spin-labeled perfusion MRI (ASL-pMRI) as an in vivo probe of cholinergic function. Ultimately, it is hoped that these techniques can be used to study the cholinergic system in vivo in normal aging, and in age-related disease states such as dementia and delirium, to further understand the cholinergic pathophysiology of these conditions, and to assist in development of more effective treatment strategies.
Fong TG, Bogardus ST Jr., Daftary A, Auerbach E, Blumenfeld H, Modur S, Leo-Summers L, Seibyl J, and Inouye SK. Cerebral perfusion changes in older delirious patients using 99mTc HMPAO SPECT. J Gerontol A Biol Sci Med Sci 2006; 61:1294-299
Alsop DC, Fearing MA, Johnson K, Sperling R, Fong TG and Inouye SK. The role of neuro-imaging in elucidating delirium pathophysiology. J Gerontol A Biol Sci Med Sci 2006; 61:1287-1293
Alsop, D.C., Casement, M. de Bazelaire, C., Fong T, Press, DZ. Hippocampal hyperperfusion in Alzheimer's disease, NeuroImage 2008. June 17
Hshieh TT, Fong TG, Marcantonio ER and Inouye SK. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci. 2008 Jul; 63(7): 764-72
