My current research work is centered on the development of magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques. This
work is divided into 2 major areas. The first is the development of methods
to acquire spatial maps of the intracellular phosphorus compounds in
skeletal muscle in vivo in diabetics and patients with peripheral vascular
disease. The second area is the development of methods for performing
high spatial resolution MRI of arterial plaques using a high magnetic
field (3 Tesla) MR scanner.
Greenman RL, Elliott MA, Vandenborne K, et al. Fast imaging of phosphocreatine using a RARE pulse sequence. Magn Reson Med 1998;39:851-854.
Greenman RL, Axel L, Ferrari VA, Lenkinski RE. Fast imaging of phosphocreatine in the normal human myocardium using a three-dimensional RARE pulse sequence at 4 Tesla. J. Magn. Reson.
Imaging. 2002;15:467-472
Greenman, RL, Shirosky, JE, Mulkern, RV, Rofsky, NM, Double inversion black-blood fast spin-exho imaging of the human heart: A comparison between 1.5T and 3.0T J Magn Reson Imaging. 2003; 17:648-655
Greenman, RL, Quantification of the 31P Metabolite Concentrations in Human Skeletal Muscle From RARE Image Intensity. Magn Reson Med. 2004; 52:1036-1042
Greenman RL, Khaodhiar L, Lima, C, Dinh T, Giurini JM, Veves A. Foot Small Muscle Atrophy is Present Before the Detection of Clinical Neuropathy. Diabetes Care. 2005; 28:1425-1430
External Recognition:
2004 American Diabetes Association Council on Foot Care Marvin Levin Scholarship Award
Major Collaborative Activities:
Phosphorus MRI of foot ulcers in diabetics - Collaborator: Dr. Aristidis
Veves, MD Joslin-BIDMC Foot Center
Evaluation of re-vascularization methods by phosphorus MRI and perfusion assessment of muscle in the lower extremites.
- Collaborator: Dr. Allen Hamdan, MD, BIDMC Department of Vascular Surgery