Title: A Multicenter Observational Study of GammaTile Surgically Targeted Radiation Therapy (STaRT) in Intracranial Brain Neoplasms

Brief Title: Observational study of GammaTiles in Brain Cancer

Title: Evaluation of Nerve Excitability in Cisplatin-Induced Peripheral Neuropathy

Brief Title: Nerve Excitability in Cisplatin-Induced Peripheral Neuropathy

Brief Summary: This study aims to evaluate nerve excitability in participants with cisplatin-induced peripheral neuropathy (cis-PN) using threshold tracking nerve conduction studies (TTNCS). By assessing changes in nerve excitability parameters, the study seeks to enhance understanding of the pathophysiology of cis-PN and identify early markers of neurotoxicity in participants undergoing cisplatin-based chemotherapy.

Title: A Phase Ib/II study of pembrolizumab, ibrutinib and rituximab in refractory/relapsed primary central nervous system lymphoma (PCNSL).

Brief Title: Pembrolizumab, Ibrutinib and Rituximab in PCNSL

Brief Summary: This research study is evaluating a combination therapy of 3 drugs as possible treatments for recurrent primary central nervous system lymphoma (PCNSL). The three drugs being used in the study are: - Pembrolizumab (MK3475) - Ibrutinib - Rituximab (or biosimilar)

Title: INdividualized Screening trial of Innovative Glioblastoma Therapy (INSIGhT)

Brief Title: INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

Brief Summary: This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : - Abemaciclib - Temozolomide (temodar) - Neratinib - CC115 - QBS10072S

Title: Retrospective Analysis of Neuroimaging in Brain Tumor Patients at BIDMC

Brief Title: Retrospective Analysis of Neuroimaging in Brain Tumor Patients at BIDMC

Title: Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate and High-Risk Meningiomas

Brief Title: Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Brief Summary: RATIONALE: Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor, such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therapy, may kill more tumor cells and cause less damage to normal tissue. It is not yet known whether observation is more effective than radiation therapy in treating patients with meningioma. PURPOSE: This phase II trial is studying observation to see how well it works compared with radiation therapy in treating patients with grade I, grade II, or grade III meningioma.

Title: A Single Patient Compassionate Use Program: Treatment of Newly Diagnosed Glioblastoma Multiforme using NovoTTF-100A

Brief Title: INDVIDUAL NOVOTTF-100A FOR PT TBD