Clinical Studies for General Medicine & Primary Care

Title: Wearable Evaluation of Ambulatory Readings for Blood Pressure
Brief Title: WEAR - BP
Brief Summary: The aim of this project is to serve as a quality control measure, assessing the accuracy and reliability of novel cuffless Blood Pressure monitoring devices. These devices will be evaluated in comparison to the established standard, Spacelabs Ambulatory Blood Pressure Monitoring (ABPM) device. This assessment is crucial to ensure the trustworthiness and suitability of the new devices for upcoming research projects. Up to 250 participants (at least 100) will be involved in this study each wearing up to 7 devices (6 BP and 1 activity monitor). The assignment of devices will be randomized by day and by the arm or wrist on which they are worn.
For info regarding 2024P000441 please contact Frederick Labri Kwapong at flarbitw@bidmc.harvard.edu
 
Title: Mindful Steps: A Web-Based Mind-Body Exercise Intervention to Promote Physical Activity in Chronic Cardiopulmonary Disease
Brief Title: Mindful Steps 20
Brief Summary: The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and/or HF. The main question it aims to answer is can this intervention promote physical activity as measured by daily step counts in sedentary patients with COPD and/or HF. Participants will be randomized (1:1 ratio) to receive either the Mindful Steps intervention or usual care for 12 months, with both arms receiving a Walking for Health education booklet.
For info regarding 2023P000595 please contact Gloria Yeh at 617-754-1419 or gyeh@bidmc.harvard.edu
 
Title: Tai Chi Exercise and Wearable Feedback Technology to Promote Physical Activity in Acute Coronary Syndrome Survivors
Brief Title: Tai Chi for ACS
Brief Summary: This projects studies the role of tai chi exercise and wearable fitness trackers to promote physical activity in acute coronary syndrome (ACS) survivors.
For info regarding 2022P000891 please contact Gloria Yeh at 617-754-1419 or gyeh@bidmc.harvard.edu
 
Title: Effects of DASH Groceries on Blood Pressure in Black Residents of Urban Food Deserts With Treated Hypertension (GoFreshRx)
Brief Title: Groceries for Black Residents of Boston to Stop Hypertension
Brief Summary: GoFreshRx is a randomized trial, testing the effects of a home-delivered DASH-patterned grocery intervention on blood pressure in Black adults actively treated for hypertension, residing in Boston area urban food deserts.
For info regarding 2022P000221 please contact Stephen Juraschek at 617-754-1416 or sjurasch@bidmc.harvard.edu
 
Title: Understanding components of mind-body exercise for physical activity engagement in metabolic syndrome: Pilot RCT
Brief Title: Mind-body exercise for physical activity
Brief Summary: The aim of this study is to assess the feasibility and acceptability (e.g., enrollment, adherence, retention, acceptability of procedures and interventions) of a pilot factorial study design that will help elucidate components of mind-body exercise interventions. The study involves completing a walking program, a mindful attention program, a walking program that includes mindful attention, or no program at all. A "pilot" study is a smaller study that helps researchers to understand whether the study design can be carried out and what participants think about the study.
For info regarding 2022P000037 please contact Kristen Kraemer at 617-754-1465 or kkraemer@bidmc.harvard.edu
 
Title: Effects of DASH Groceries on Blood Pressure in Black Residents of Urban Food Deserts Without Treated Hypertension
Brief Title: Groceries for Black Residents of Boston to Stop Hypertension
Brief Summary: GoFresh is a randomized trial, testing the effects of a home-delivered DASH-patterned grocery intervention on blood pressure in Black adults, residing in Boston area urban food deserts.
For info regarding 2021P000825 please contact Stephen Juraschek, MD PhD at 617-903-7943 or gofresh@bidmc.org
 
Title: Neurophysiological Patterns of mindfulness meditation for Insomnia
Brief Title: Mindfulness meditation for Insomnia
Brief Summary: This is a pilot study evaluating the feasibility and acceptability of a non-pharmacological, mind-body intervention to improve sleep quality, including a preliminary evaluation of neurophysiological signals. The study involves 4 weeks of guided mind-body practice at home using a smartphone app during bedtime and pre/post in-lab sleep study visits.
For info regarding 2019P000984 please contact Ivy Ma at yma3@bidmc.harvard.edu