Clinical Studies for Nephrology

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Title: Development of a clinical experimental heat stress protocol and exploration of the effect of Niacinamide on physiologic, metabolic, and biochemical responses to heat stress

Brief Title: Experimental heat stress metabolomics and the effect of Nam

Brief Summary:

PI: Nathan Raines, MD

Group: Nephrology

Study Start: 5/5/2025

End: 6/1/2028

Gender: All

Age Range: 18 years to 100 Years

Recruit Healthy Volunteers: Yes

ID: NCT06983730

For info regarding 2024P000637 please contact Nathan Raines at 617-632-9880 or nraines@bidmc.harvard.edu

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Title: A Phase 2/3 Adaptive, Double-blind, Placebo- Controlled Study to Evaluate the Efficacy and Safety of VX-147 in Adults and Pediatric Subjects With APOL1-mediated Proteinuric Kidney Disease

Brief Title: Phase 2/3 Adaptive Study of VX-147 in Adults With APOL1-medi

Brief Summary: The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease.

PI: Bradley Denker, MD

Group: Nephrology

Study Start: 7/18/2022

End: 5/31/2026

Gender: All

Age Range: 10 Years to 65 Years

Recruit Healthy Volunteers: No

ID: NCT05312879

For info regarding 2022P000526 please contact Liz Roy at (617) 975-8684 or eroy2@bidmc.harvard.edu

View on ClinicalTrials.Gov

Clinical Trials Displayed: 2