Clinical Studies for Pulmonary, Critical Care & Sleep Medicine

Title: A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study Evaluating the Safety and Efficacy of Pirfenidone Solution for Inhalation (AP01) in Subjects with Progressive Pulmonary Fibrosis (PPF)
Brief Title: A Randomized, Placebo-Controlled, Study with Pirfenidone Sol
Brief Summary: A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
For info regarding 2024P000407 please contact Sean Levy at 617-726-8554 or sdlevy@bidmc.harvard.edu
 
Title: A prospective, multicenter, randomized, and controlled study to evaluate the safety and effectiveness of the STIMIT ACTIVATOR 1 System
Brief Title: STIMIT
Brief Summary: The study is a prospective, multi-center, randomized, controlled study using adaptive design to assess the evidence of safety and performance of the STIMIT Activator 1 System in the treatment of patients who have been mechanically ventilated for up to 48 hours and are predicted to require additional minimum 48 hours of mechanical ventilation or longer (adding up to MV time approximately 96 hours or longer).
For info regarding 2023P000981 please contact Elias Baedorf Kassis at 617-667-0000 or enbaedor@bidmc.harvard.edu
 
Title: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of DWN12088 in Patients With Idiopathic Pulmonary Fibrosis
Brief Title: DaeWoong DWN12088
Brief Summary: This is a randomized, double-blinded, placebo-controlled multicenter study to evaluate the safety and efficacy of DWN12088 in patients with Idiopathic Pulmonary Fibrosis.
For info regarding 2023P000113 please contact Clinical Research Center at 617-975-7600 or crc@bidmc.harvard.edu
 
Title: Targeted group-based psychotherapy to address emotional stress in at risk ICU-survivors: A pilot feasibility study
Brief Title: Addressing mental health in ICU-survivors
Brief Summary: This study is a pilot clinical trial to assess the feasibility of implementing a group-psychotherapy intervention to modify emotional stress (e.g., anxiety, depression, post-traumatic stress) following ICU hospitalization
For info regarding 2023P000087 please contact Katherine Berg at 617-667-5864 or kberg@bidmc.harvard.edu
 
Title: A Randomized Controlled Trial of Home Air Purification for Eosinophilic COPD
Brief Title: HEPA RCT in COPD
Brief Summary: This study evaluates the influence of home air purification on the lung health of adults with eosinophilic COPD. Half of the participants will receive real air purifiers (HEPA filters) and half will receive sham air purifiers.
For info regarding 2019P001129 please contact Mary Rice at 617-667-0000 or mrice1@bidmc.harvard.edu