Title: RAPID-PE Study: RESCUE Advanced Protocol without ICU stay and no lytic Drip - for the Treatment of Pulmonary Embolism

Brief Title: RAPID-PE Study

Brief Summary: To demonstrate the efficacy and safety of the 8F BASHIR™ .035 Endovascular Catheter and the 8F BASHIR™ S-B .035 Endovascular Catheter for the administration of pharmaco-mechanical catheter directed therapy using pulse sprays of r-tPA into the pulmonary arteries for the treatment of intermediate risk pulmonary embolism (PE).

Title: A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism (ENGULF)

Brief Title: ENGULF

Brief Summary: Evaluation of initial safety and clinical feasibility of the Helo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).

Title: MRI Evaluation of Aging Related Changes to the Brain

Brief Title: MRI Evaluation of Aging Related Changes to the Brain

Brief Summary: The purpose of this study is to develop new magnetic resonance imaging (MRI) techniques that can be used to clinically evaluate patients across a spectrum of ages 18+. This study will test magnetic resonance techniques on FDA approved MRI machines. Newly developed MRI sequences will be validated on normal subject brains and compared to standard techniques. This study will evaluate different brain imaging techniques including Arterial Spin Labeling (ASL) perfusion and Inhomogeneous Magnetization Transfer (ihMT) imaging.