Patrick Fuller, PhD
Non Paid Employee_BIDMC
Research Operations
Neurology
Contact Information
| Office: | CL-0644 |
| Phone: | 617-735-2811 |
| Fax: | 617-735-2910 |
| Email: | pfuller@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; CL-0644
Boston, MA 02215 |
Areas of Interest
| 3 Neuroscience |
Major Research Theme
|
From an investigational standpoint, our laboratory is interested in defining the neuronal substrates regulating behavioral state control, including key nodes, their transmitters and their targets. This work spans a significant continuum and includes lines of investigation involving sleep and circadian regulation to mechanisms of anesthesia to circuitry supporting neurobehavioral and electrocortical arousal (i.e., wakeful consciousness). Investigative approaches include chronic telemetry, ISH, RTqPCR, microarrays, IHC, behavioral recordings, modeling, neuronal tracers, neurotoxic lesions, genetically modified mice (transgenic, knockin, knockout), pharmacogenetics and the development of cre-dependent AAV approaches for the targeted and cell-type specific placement of genetically engineered channel-receptor systems. The ultimate goal of our work is to link the in vivo activity of defined sets of neurons with neurobehavioral and physiological outcomes in freely behaving animals. |
Publications
Major Collaborative Activities
| Dr. Clifford Saper (Neurology, BI) |
Investigator's Lab Web Site
| Research Lab URL | None listed |
| Harvard Catalyst Site: | Fuller Harvard Catalyst Web Site |
