Winston Hide, PhD
Principal Investigator
Pathology
Pathology
Contact Information
| Office: | DA-0519 |
| Phone: | 617-667-4145 |
| Fax: | |
| Email: | whide@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; DA-0519
Boston, MA 02215 |
Research Lab Team Members
| Isabel Castanho PhD | Pourya Naderi Yeganeh PhD |
Areas of Interest
| 3 Neuroscience |
Major Research Theme
| It is not individual genes, but rather biological pathway signaling through interacting networks of genes that drive disease and response to the environment. My group builds interaction maps of genes and pathways. We define modules and changes in these maps using genomic variants, functional 'omics assays and correlated phenotypes to deliver causal mechanisms that can be actioned by drug interventions. In turn we build connection maps between drug responses and pathways - performing quantitative systems pharmacology in silico to prioritize drugs and their targets. We are integrating noncoding RNA maps into these functional interactions to yield an RNA systems medicine approach to drug development. |
Publications
External Recognition
| 1998 National President’s Award, Foundation for Research Development, South Africa 2007 Winner, Oppenheimer Foundation Distinguished Sabbatical Research Fellowship 2011 Award for Outstanding Achievement, First International Society for Computational Biology award 2010-2012 Co-founder, Steering Committee Human Heredity and Health Genome Project, Africa |
Major Collaborative Activities
| Driving development of the BIDMC Data Science Initiative Co-Director noncoding RNA Therapeutics Core |
Investigator's Lab Web Site
| Research Lab URL | Hide Research Lab |
| Harvard Catalyst Site: | None found |
