Steven P Balk, MD,PhD
Professor
Hematology Oncology
Contact Information
| Office: | CL-0443 |
| Phone: | 617-735-2065 |
| Fax: | 617-667-0610 |
| Email: | sbalk@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; CL-0443
Boston, MA 02215 |
Research Lab Team Members
| Shaoyong Chen PhD | Xin Yuan MD,PhD |
Areas of Interest
| 1 Cancer |
Major Research Theme
| Our major disease interest is prostate cancer, with a particular focus on the role of the androgen receptor in prostate cancer development and progression. We are studying molecular mechanisms of androgen receptor action in normal prostate and prostate cancer. These include studies of AR structure, AR mutations, DNA binding, and interactions with coactivator/corepressor proteins. The lab has identified several androgen interacting proteins, and a long term objective is to develop novel androgen receptor antagonists that will selectively modulate androgen receptor protein interactions. Other objectives are to establish animal models of prostate cancer and to carry out translational studies on clinical materials from prostate cancer patients. |
Publications
External Recognition
| 1987 NCI, Physician Scientist Award, 7/87-6/90 1992 American Cancer Society Junior Faculty Research Award 1995 American Society for Clinical Investigation 1997, 99, 01 ad hoc member NIH Biochemical Endocrinology Study Section 2001, 02 ad hoc member NIH Immunological Sciences and Experimental Immunology Study Sections 1999-2002 Department of Defense Prostate Cancer Study Section |
Major Collaborative Activities
| Dana Farber/Harvard Cancer Center Prostate Cancer SPORE |
Investigator's Lab Web Site
| Research Lab URL | None listed |
| Harvard Catalyst Site: | Balk Harvard Catalyst Web Site |
