Cornelis P Terhorst, PhD
Division Chief
Immunology
Contact Information
| Office: | CL-0938 |
| Phone: | 617-735-4131 |
| Fax: | 617-735-4135 |
| Email: | cterhors@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; CL-0938
Boston, MA 02215 |
Research Lab Team Members
| Ninghai Wang MD,PhD |
Areas of Interest
| 1 Cancer |
Major Research Theme
|
The Division of Immunology is a basic science research division that works with academic physicians in subspecialties to study primary immunodeficiencies, the role of innate and adaptive immunology in the pathogenesis of autoimmune disorders (e.g, lupus and inflammatory bowel disease). Researchers in the Division, employing the latest advances in genetic research, are investigating at the most basic levels the mechanisms of signal transduction initiated upon engagement of a series of distinct immune receptors. Some of their discoveries have proven to be directly applicable to the diagnosis and treatment of human diseases. Specific Interests are: 1. Pathogenesis of the X-linked Lympho-Proliferative disease syndrome. 2. The SLAM and SLAM Gene Familes control innate and adaptive immune responses to viruses and bacteria. 3. Studies of the pathogenesis of experimental Inflammatory Bowel Disease. 4. Role of the SLAM family genes in experimental SLE. |
Publications
External Recognition
| -Associate Director Center for the Study of Inflammatory Bowel Diseases, Harvard Medical School. -Associate Director Harvard Center for the Study of Primary Immunodeficiencies. -Scientific Advisory Board of The Wistar Institute of Philadelphia. -Scientific Advisory Board of The MD Anderson Cancer Center (Houston). -Advisor to the Immunology Platforms, Novartis. -Grant Review Committee MOD, CCFA, FIRB (Italian Government), KWF (Dutch Cancer Institute). |
Major Collaborative Activities
| SLE: George Tsokos (BIDMC) Primary Immunodeficiencies: Fred Alt, Luigi Notarangelo and Raif Geha at The Childrens Hospital IBD: Dan Podolsky and Atul Bhan (MGH) , Rick Blumberg and Dennis Kasper (BWH) |
Investigator's Lab Web Site
| Research Lab URL | Terhorst Research Lab |
| Harvard Catalyst Site: | Terhorst Harvard Catalyst Web Site |