David E Avigan, MD
Professor
Hematology Oncology
Contact Information
| Office: | KS-0134 |
| Phone: | 617-667-9920 |
| Fax: | 617-667-9922 |
| Email: | davigan@bidmc.harvard.edu |
| Address: | 330 Brookline Ave; KS-0134
Boston, MA 02215 |
Advanced Degree And Training
| Year | Institution | Area or Rank |
| 1989 | Yale School of Medicine | Medicine |
| 1989 | Columbia Presbyterian Hospital | Internal Medicine Residen |
| 1992 | Columbia Presbyterian Hospital | Chief Medical Resident |
| 1993 | Memorial Sloan Kettering Cancer Center | Hematology/Oncology Fello |
| 1994 | Memorial Sloan Kettering Cancer Center | Chief Fellow |
| 1994 | Rockefeller University | Research Associate |
Areas of Interest
| 1 Cancer |
Major Research Theme
| The focus of my research efforts has been in the field of dendritic cell cancer vaccines. We have developed a model in which tumor cells are fused to immune stimulating dendritic cells and then used to induce an anti-tumor response. After publishing work in pre-clinical models, I have filed an IND to study this vaccine in patients with cancer and have conducted several trials using a vaccine this is being produced in our stem cell/ immunotherapy facility. Trials and pre-clinical work is ongoing. As director of the Hematological Malignancy and Bone Marrow Transplant Program, I am also conducting research in post-transplant immune recovery and in several areas of clinical research in hematological malignancies and transplant. |
Publications
External Recognition
| • ECOG Leukemia and Bone Marrow Transplant Committee • Project Leader Renal Spore, Skin Spore • Invited speaker, “Dendritic cell/Tumor fusion vaccinesâ€, International Symposium On Cancer Vaccines, Washington, DC, 2006 • Invited speaker, “Dendritic cell/Multiple Myeloma Fusion vaccinesâ€, Leukemia and Lymphoma Society Translational Research Meeting, San Diego, 2006 • Invited speaker, “Dendritic Cell/Tumor Fusions for Patients with Multiple Myelomaâ€, Keystone Conference American Society of Bone Marrow Transplantation/International Bone Marrow Transplantation Registry Conference, 2007 • Oral presentation, “Phase I Study of Vaccination with DC/Myeloma Fusionsâ€, American Society of Hematology, 2007 • Oral presentation, “Vaccination with DC/Myeloma Fusions in Conjunction with Stem Cell Transplantationâ€, American Society of Hematology, 2007 • Invited speaker, “Targeted Therapy for AMLâ€, Virginia Beach Oncology, 2007 • Visiting Professor and Invited Speaker, “Dendritic Cell Cancer Vaccine from the Bench to the Bedsideâ€, Case Western Reserve Medical Center, 2007 • Oral presentation, “Vaccination with DC/Myeloma Fusions in Conjunction with Stem Cell Transplantationâ€, American Society of Bone Marrow Transplantation, 2008 • Best of American Society of Oncology: Review of Leukemia/Myeloproliferative Disease/Myelodysplasia, Boston MA, 2008 |
Major Collaborative Activities
| Member of Immunology, Transplant, and Leukemia Program at Harvard Cancer Center Cancer Vaccine Program: Laboratory work and collaboration with Dr. Donald Kufe, DFCI |
Investigator's Lab Web Site
| Research Lab URL | None listed |
| Harvard Catalyst Site: | Avigan Harvard Catalyst Web Site |
